Breed-related ventriculomegaly isn’t normal

Mild to moderate ventriculomegaly is common in brachycephalic breeds. It's long been assumed that this was a "normal" breed variation, but a recent study suggests it may not be normal. Click on post title to read more.

Characteristics of Scottie Cramp

This recent manuscript out of North Carolina State University describes the clinical findings and treatment outcome of Scottie Cramp in 31 dogs. Click on post title to read a synopsis of the article.

Prevalence, heritability & outcome of syringomyelia in Cavaliers

This manuscript describes a three-phase study investigating the prevalence, heritability, and outcome of syringomyelia (SM) in all Cavalier King Charles Spaniels...Click on the post title to read more.

Phenobarbital lowers serum levetiracetam concentrations

This was a prospective pharmacokinetic study that evaluated the effects of chronic administration of phenobarbital, bromide, or the combination on serum concentrations of levetiracetam (LEV; Keppra) in epileptic dogs.

Journal club: Transdermal phenobarbital in cats

This was a prospective clinical study to determine serum phenobarbital concentration after transdermal application.

COTM: Painful & ataxic Cavalier

The patient was referred for progressive neurologic signs. He started scratching his abdomen about 3 weeks prior to referral. There was no response to a course of oral cefpodoxime and topical antibiotic spray. He was taken to the ER department of another local specialty hospital 5 days later for suspected pain and inappetance.